HSPE1P10

Across TCGA pan-cancer cohorts, HSPE1P10 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated HSPE1P10 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HSPE1P10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSPE1P10 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CHOL show a favorable association.

KIRC, KIRP, and HNSC are the cancer types where HSPE1P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	III,IV	0.497	0.695	<.001	148	view →
KIRP	OS	Median	All	0.880	0.979	<.001	43	view →
HNSC	OS	Median	IV	0.744	0.586	.013	37	view →
CHOL	OS	Tertile	All	1.000	0.309	.012	30	view →
ESCA	DFS	Quartile	All	0.126	1.000	<.001	29	view →
BRCA	OS	Median	III,IV	0.845	0.932	.010	21	view →
BLCA	DFS	Tertile	III,IV	0.192	0.427	.012	20	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
ACC	DFS	Quartile	All	0.523	0.814	.014	15	view →
LIHC	DFS	Quartile	All	0.307	0.570	.001	14	view →
READ	OS	Tertile	III,IV	0.746	0.961	.006	12	view →
CESC	DFS	Tertile	II,III,IV	0.550	0.744	.026	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

HSPE1P10–KIRC (DFS)

Open the KIRC breakdown →