HSPE1

Across TCGA pan-cancer cohorts, HSPE1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HSPE1 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HSPE1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HSPE1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where HSPE1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.919	.013	42	view →
PDAC	DFS	Median	II,III,IV	0.487	0.258	.005	23	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	9	view →
LSCC	OS	Tertile	II,III,IV	1.000	0.831	.022	7	view →
CCRCC	DFS	Quartile	III,IV	0.260	0.643	.013	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HSPE1–COAD (DFS)

Open the COAD breakdown →