HSPD1P12

Across TCGA patient cohorts, HSPD1P12 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,562 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPD1P12-associated proteins across cancer lineages are SQSTM1_T269, ARHGAP25_T443, and MAPKAPK2. Each is linked with HSPD1P12 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSPD1P12-to-partner and partner-to-HSPD1P12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPD1P12 versus SQSTM1_T269 in GBM, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPD1P12→partner) and Y-score (partner→HSPD1P12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SQSTM1_T269 →	-0.804	-0.365	<.001	<.001	3	3
OV	ARHGAP25_T443 →	-1.075	-1.060	<.001	.001	3	3
OV	MAPKAPK2 →	-0.276	-0.793	<.001	.001	3	3
BRCA	ALB →	-0.821	-0.664	<.001	<.001	3	3
GBM	GBE1 →	-0.369	-0.304	<.001	.003	3	3
GBM	MVB12B_S309 →	+0.414	+0.328	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,562 associations by consensus.

HSPD1P12 vs SQSTM1_T269 — GBM

Explore this scatter interactively →