HSPD1P12

Across TCGA pan-cancer cohorts, HSPD1P12 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated HSPD1P12 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher HSPD1P12 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPD1P12 expression acts as an unfavorable survival marker, although some lineages such as HNSC and READ show a favorable association.

UVM, LUAD, and OV are the cancer types where HSPD1P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Quartile	III,IV	0.474	0.881	.005	59	view →
LUAD	DFS	Median	III,IV	0.483	0.745	.006	33	view →
OV	OS	Tertile	III,IV	0.621	0.731	.016	20	view →
CHOL	OS	Tertile	III,IV	0.136	0.859	.003	18	view →
ESCA	DFS	Median	All	0.538	0.908	.025	18	view →
LIHC	OS	Quartile	III,IV	0.169	0.652	.003	18	view →
HNSC	DFS	Quartile	III,IV	0.686	0.422	.020	17	view →
KIRP	OS	Quartile	All	0.505	0.808	.002	17	view →
THYM	DFS	Median	III,IV	0.214	1.000	.008	15	view →
UCS	OS	Quartile	All	0.601	0.831	.026	10	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →
KIRC	DFS	Quartile	IV	0.180	0.359	.032	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

HSPD1P12–UVM (OS)

Open the UVM breakdown →