HSPB9

Across TCGA patient cohorts, HSPB9 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSPB9-associated genes across cancer lineages are MIR874, TTC24, and SUCNR1. Each is linked with HSPB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPB9-to-partner and partner-to-HSPB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR874 grouped by HSPB9-low versus HSPB9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB9→partner) and Y-score (partner→HSPB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR874 →	+0.335	+3.053	.001	.003	3	2
UCEC	TTC24 →	+0.319	+3.223	.002	.009	3	1
UCEC	SUCNR1 →	+0.554	+3.223	.003	.009	3	1
UCEC	RNU4-82P →	+0.449	+2.729	.002	.004	3	1
UCEC	RNU6-859P →	+0.509	+2.538	.002	.008	3	1
UCEC	RNA5SP260 →	+0.688	+3.173	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

MIR874 by HSPB9 expression — UCEC

Explore this box plot interactively →