HSPB8

Across TCGA patient cohorts, HSPB8 protein abundance is significantly associated with the RNA expression of many other genes, with 14,520 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPB8-associated genes across cancer lineages are EFEMP1, KIF11, and CDCA5. Each is linked with HSPB8 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPB8-to-partner and partner-to-HSPB8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB8 versus EFEMP1 in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB8→partner) and Y-score (partner→HSPB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EFEMP1 →	+1.425	+0.574	<.001	<.001	3	7
LSCC	KIF11 →	-0.771	-0.549	<.001	<.001	3	7
LUAD	CDCA5 →	-0.876	-0.360	<.001	.001	3	7
GBM	BUB1 →	-0.850	-0.524	<.001	<.001	3	7
LUAD	CDCA2 →	-1.038	-0.390	<.001	<.001	3	7
GBM	DEPDC1 →	-0.998	-0.781	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,520 associations by consensus.

HSPB8 vs EFEMP1 — OV

Explore this scatter interactively →