HSPB8

Across TCGA cell cohorts, HSPB8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,802 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HSPB8-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Viral process. Each is linked with HSPB8 in more than 12 cancer types. Because this analysis shows association rather than direction, both HSPB8-to-partner and partner-to-HSPB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by HSPB8-low versus HSPB8-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB8→partner) and Y-score (partner→HSPB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Process utilizing autophagic mechanism →	+0.086	+2.924	<.001	<.001	3	13
STOMACH	Autophagy →	+0.086	+2.924	<.001	<.001	3	13
STOMACH	Viral process →	+0.101	+3.164	<.001	<.001	3	11
OESOPHAGUS	Macroautophagy →	+0.085	+2.561	<.001	.003	2	12
LIVER	Negative regulation of transforming growth factor beta production →	+0.337	+3.600	<.001	<.001	3	11
LARGE_INTESTINE	Protein targeting to vacuole involved in autophagy →	+0.130	+1.245	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,802 associations by consensus.

Process utilizing autophagic mechanism by HSPB8 expression — STOMACH

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