HSPB6

Across TCGA patient cohorts, HSPB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,923 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSPB6-associated proteins across cancer lineages are OGN, MYH11, and MYLK. Each is linked with HSPB6 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSPB6-to-partner and partner-to-HSPB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB6 versus OGN in CCRCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB6→partner) and Y-score (partner→HSPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	OGN →	+1.217	+0.702	<.001	<.001	3	9
UCEC	MYH11 →	+1.175	+1.560	<.001	<.001	3	8
UCEC	MYLK →	+0.998	+1.422	<.001	<.001	3	8
UCEC	OLFML1 →	+1.187	+1.517	<.001	<.001	3	8
OV	OLFML3 →	+1.239	+1.305	<.001	<.001	3	8
UCEC	PRKG1 →	+0.924	+1.391	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,923 associations by consensus.

HSPB6 vs OGN — CCRCC

Explore this scatter interactively →