HSPB6

Across TCGA patient cohorts, HSPB6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,985 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HSPB6-associated genes across cancer lineages are CDO1, SGCA, and AOC3. Each is linked with HSPB6 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSPB6-to-partner and partner-to-HSPB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB6 versus CDO1 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB6→partner) and Y-score (partner→HSPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDO1 →	+1.648	+0.908	<.001	<.001	3	10
HNSC	SGCA →	+1.446	+1.092	<.001	<.001	3	9
BRCA	AOC3 →	+1.506	+1.116	<.001	<.001	3	9
BRCA	ABCA8 →	+1.231	+0.928	<.001	<.001	3	9
CCRCC	ABCA6 →	+0.928	+1.205	<.001	<.001	3	9
UCEC	JAM2 →	+1.022	+0.854	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,985 associations by consensus.

HSPB6 vs CDO1 — UCEC

Explore this scatter interactively →