HSPB6

Across TCGA cell cohorts, HSPB6 RNA expression is significantly associated with the RNA expression of many other genes, with 5,296 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HSPB6-associated genes across cancer lineages are HTRA1, CSPG4, and NPR2. Each is linked with HSPB6 in more than 4 cancer types. Because this analysis shows association rather than direction, both HSPB6-to-partner and partner-to-HSPB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPB6 versus HTRA1 in BONE, with a Pearson correlation of 0.74.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB6→partner) and Y-score (partner→HSPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	HTRA1 →	+5.430	+4.026	<.001	<.001	3	4
BONE	CSPG4 →	+2.721	+2.450	<.001	<.001	3	4
BONE	NPR2 →	+1.961	+3.679	<.001	.002	3	4
BONE	PLPP7 →	+1.276	+2.432	<.001	<.001	3	4
SOFT_TISSUE	THBS3 →	+1.794	+2.152	<.001	.003	2	5
URINARY_TRACT	CMTM1 →	+0.855	+0.409	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,296 associations by consensus.

HSPB6 vs HTRA1 — BONE

Explore this scatter interactively →