HSPB6

Across TCGA cell cohorts, HSPB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,255 significant associations in total. CNS shows the largest number of these associations.

The most reproducible HSPB6-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with HSPB6 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPB6-to-partner and partner-to-HSPB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by HSPB6-low versus HSPB6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPB6→partner) and Y-score (partner→HSPB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Calcium-independent cell-matrix adhesion →	+0.165	+1.896	<.001	.008	3	7
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+0.723	<.001	.002	3	7
SKIN	Negative regulation of myoblast fusion →	+0.089	+0.769	<.001	.001	3	6
CNS	Positive regulation of cell-substrate junction organization →	+0.086	+1.440	<.001	<.001	3	6
SKIN	Cilium or flagellum-dependent cell motility →	-0.043	-0.490	.001	.004	3	6
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to plasma membrane →	+0.067	+0.248	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,255 associations by consensus.

Calcium-independent cell-matrix adhesion by HSPB6 expression — SOFT_TISSUE

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