HSPA9

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSPA9 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,958 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA9-associated proteins across cancer lineages are GEMIN5, HSPA4, and TRAP1. Each is linked with HSPA9 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPA9-to-partner and partner-to-HSPA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA9 versus GEMIN5 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA9→partner) and Y-score (partner→HSPA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGEMIN5 →+0.312+0.851<.001<.00137
OVHSPA4 →+0.366+0.593<.001<.00137
LSCCTRAP1 →+0.536+0.496<.001<.00137
LSCCLARP1 →+0.294+0.520<.001<.00137
OVPHAX →+0.352+0.606<.001<.00136
LSCCUSP10_S547 →+0.737+0.506<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,958 associations by consensus.

HSPA9 vs GEMIN5 — HNSC

Per-sample scatter of HSPA9 vs GEMIN5 in HNSC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration