heat shock protein family A (Hsp70) member 8 pseudogene 4Genealiases: []
Q-omics provides the consensus-scored HSPA8P4 profile across patient tissues and cancer cell-line models. HSPA8P4 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, HSPA8P4 is differentially expressed in 11, with the highest sampling consensus in KIRC. Additionally, HSPA8P4 RNA expression shows 15,505 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight MESO, KIRC, and UVM as cancer lineages where HSPA8P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSPA8P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSPA8P4 survival associations across molecular data types. HSPA8P4 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSPA8P4 RNA expression–survival associations across cancer types. High HSPA8P4 expression shows unfavorable associations in MESO, UVM and THCA, but favorable associations in LUAD, UCS and HNSC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify MESO as the clearest survival context for HSPA8P4 RNA expression.
This table summarizes HSPA8P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for HSPA8P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSPA8P4 shows lower tumor expression in THCA and higher tumor expression in KIRC, HNSC, COAD, BRCA and READ. The KIRC box plot shows higher HSPA8P4 RNA expression in tumor versus normal tissue (log2 FC = +0.184, t-test p < 0.001).
This table shows molecular features associated with HSPA8P4 in patient tissues and cancer cell lines. In patient samples, HSPA8P4 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
