Across TCGA pan-cancer cohorts, HSPA8P16 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated HSPA8P16 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher HSPA8P16 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSPA8P16 expression acts as an unfavorable survival marker, although some lineages such as LUSC and THYM show a favorable association.

LIHC, BRCA, and DLBC are the cancer types where HSPA8P16 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.698	0.849	.001	72	view →
BRCA	DFS	Tertile	All	0.864	0.932	<.001	56	view →
DLBC	DFS	Tertile	II,III,IV	0.429	0.971	.006	30	view →
UCEC	DFS	Median	II,III,IV	0.648	0.799	.005	30	view →
KIRC	DFS	Quartile	IV	0.195	0.439	.004	24	view →
ESCA	DFS	Median	II,III,IV	0.374	1.000	.006	22	view →
ACC	OS	Tertile	All	0.677	0.934	.017	21	view →
STAD	OS	Quartile	III,IV	0.181	0.583	<.001	18	view →
LUSC	DFS	Quartile	All	0.837	0.690	.001	18	view →
SKCM	DFS	Median	II,III,IV	0.495	0.624	.003	15	view →
COAD	DFS	Median	IV	0.359	0.615	.014	15	view →
THYM	DFS	Median	All	0.932	0.662	.019	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration

Same gene, other analysis: HSPA8P16 tumor-vs-normal RNA expression · all HSPA8P16 data types