HSPA8

Across TCGA patient cohorts, HSPA8 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,968 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA8-associated proteins across cancer lineages are EIF4G1, G3BP1, and HYI. Each is linked with HSPA8 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPA8-to-partner and partner-to-HSPA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA8 versus EIF4G1 in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA8→partner) and Y-score (partner→HSPA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EIF4G1 →	+0.308	+0.450	<.001	<.001	3	6
UCEC	G3BP1 →	+0.220	+1.019	<.001	<.001	3	5
OV	HYI →	-0.365	-0.691	.001	.002	3	5
LSCC	NUFIP2 →	+0.219	+0.367	<.001	<.001	3	5
OV	CHORDC1 →	+0.333	+0.596	.003	.001	3	5
OV	LARP1 →	+0.278	+0.698	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,968 associations by consensus.

HSPA8 vs EIF4G1 — LSCC

Explore this scatter interactively →