HSPA6

Across TCGA patient cohorts, HSPA6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,464 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSPA6-associated proteins across cancer lineages are PPP1R18_S224, ITGB2, and ATE1. Each is linked with HSPA6 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPA6-to-partner and partner-to-HSPA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA6 versus PPP1R18_S224 in LUAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA6→partner) and Y-score (partner→HSPA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPP1R18_S224 →	+0.513	+0.936	.004	.004	3	7
OV	ITGB2 →	+0.559	+0.697	<.001	.005	3	7
OV	ATE1 →	-0.267	-0.693	.002	.009	3	7
GBM	FCER1G →	+0.693	+1.380	<.001	<.001	3	7
GBM	HK3 →	+1.149	+1.519	<.001	<.001	3	7
GBM	NCF4 →	+0.491	+1.391	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,464 associations by consensus.

HSPA6 vs PPP1R18_S224 — LUAD

Explore this scatter interactively →