HSPA6

Across TCGA cell cohorts, HSPA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,043 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSPA6-associated GO terms across cancer lineages are Peripheral nervous system myelin maintenance, Viral process, and Negative regulation of protein catabolic process. Each is linked with HSPA6 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSPA6-to-partner and partner-to-HSPA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peripheral nervous system myelin maintenance grouped by HSPA6-low versus HSPA6-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA6→partner) and Y-score (partner→HSPA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Peripheral nervous system myelin maintenance →	+0.200	+0.661	<.001	.001	3	9
LUNG_NSCLC_LUAD	Viral process →	+0.045	+0.614	<.001	.002	3	8
STOMACH	Negative regulation of protein catabolic process →	+0.073	+0.508	.009	.001	3	8
LARGE_INTESTINE	Negative regulation of glial cell differentiation →	+0.128	+0.586	<.001	<.001	3	7
BLOOD_Leukemia	Hemidesmosome assembly →	+0.250	+0.588	.008	.007	3	7
BREAST	Cellular response to nutrient levels →	+0.029	+0.457	.003	.006	1	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,043 associations by consensus.

Peripheral nervous system myelin maintenance by HSPA6 expression — BREAST

Explore this box plot interactively →