Across TCGA pan-cancer cohorts, HSPA5P1 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated HSPA5P1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher HSPA5P1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated HSPA5P1 expression acts as an unfavorable survival marker.

OV are the cancer types where HSPA5P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	All	0.244	0.690	.006	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: HSPA5P1 tumor-vs-normal RNA expression · all HSPA5P1 data types