HSPA4L

Across TCGA patient cohorts, HSPA4L RNA expression is significantly associated with the protein abundance of many other proteins, with 13,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA4L-associated proteins across cancer lineages are HSPA4L_T545, H6PD, and KIF21A. Each is linked with HSPA4L in more than 5 cancer types. Because this analysis shows association rather than direction, both HSPA4L-to-partner and partner-to-HSPA4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA4L versus HSPA4L_T545 in LSCC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4L→partner) and Y-score (partner→HSPA4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HSPA4L_T545 →	+1.064	+1.243	<.001	<.001	3	6
BRCA	H6PD →	-0.399	-0.779	.001	.001	3	5
LSCC	KIF21A →	+0.337	+0.709	<.001	<.001	3	5
UCEC	RRM1 →	+0.587	+0.788	<.001	<.001	3	4
COAD	ACSL5 →	-0.672	-1.176	<.001	<.001	3	4
HNSC	SDAD1_S459 →	+0.689	+0.805	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,938 associations by consensus.

HSPA4L vs HSPA4L_T545 — LSCC

Explore this scatter interactively →