HSPA4L

Across TCGA patient cohorts, HSPA4L protein abundance is significantly associated with the RNA expression of many other genes, with 15,279 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA4L-associated genes across cancer lineages are IFFO1, GRPEL1, and LUM. Each is linked with HSPA4L in more than 4 cancer types. Because this analysis shows association rather than direction, both HSPA4L-to-partner and partner-to-HSPA4L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA4L versus IFFO1 in OV, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4L→partner) and Y-score (partner→HSPA4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IFFO1 →	-0.857	-0.525	.001	.005	3	5
OV	GRPEL1 →	+0.679	+0.625	<.001	<.001	3	5
OV	LUM →	-1.552	-0.505	.009	.006	3	5
OV	DPT →	-1.309	-0.413	<.001	.003	3	5
OV	ENOPH1 →	+0.509	+0.592	.001	.002	3	5
OV	IL2RG →	-1.174	-0.482	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,279 associations by consensus.

HSPA4L vs IFFO1 — OV

Explore this scatter interactively →