HSPA4L

Across TCGA cell cohorts, HSPA4L mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HSPA4L-associated genes across cancer lineages are CIB4, LRRC52, and ANKRD40CL. Each is linked with HSPA4L in more than 1 cancer types. Because this analysis shows association rather than direction, both HSPA4L-to-partner and partner-to-HSPA4L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CIB4 grouped by HSPA4L-low versus HSPA4L-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4L→partner) and Y-score (partner→HSPA4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CIB4 →	+0.201	+4.209	<.001	.001	3	1
BLOOD_Lymphoma	LRRC52 →	+0.653	+3.342	<.001	.008	3	1
BLOOD_Lymphoma	ANKRD40CL →	+0.494	+3.506	.001	.008	3	1
BLOOD_Lymphoma	GLOD5 →	+0.053	+3.321	<.001	.006	3	1
BLOOD_Lymphoma	OR11H4 →	+0.031	+3.959	<.001	.002	3	1
BLOOD_Lymphoma	PRM3 →	+0.112	+4.129	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CIB4 by HSPA4L expression — BLOOD_Lymphoma

Explore this box plot interactively →