HSPA4

Across TCGA patient cohorts, HSPA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSPA4-associated proteins across cancer lineages are YTHDC2, KDM3B, and LARP1. Each is linked with HSPA4 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSPA4-to-partner and partner-to-HSPA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSPA4 versus YTHDC2 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSPA4→partner) and Y-score (partner→HSPA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YTHDC2 →	+0.282	+0.608	<.001	<.001	3	7
OV	KDM3B →	+0.309	+0.477	<.001	<.001	3	7
LSCC	LARP1 →	+0.247	+0.396	<.001	<.001	3	7
GBM	CAPRIN1 →	+0.287	+0.249	.001	.008	3	7
LSCC	G3BP1 →	+0.301	+0.536	<.001	<.001	3	7
HNSC	GEMIN5 →	+0.274	+0.940	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,947 associations by consensus.

HSPA4 vs YTHDC2 — OV

Explore this scatter interactively →