HSP90B2P

Across TCGA pan-cancer cohorts, HSP90B2P RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated HSP90B2P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher HSP90B2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HSP90B2P expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

ACC, SKCM, and KICH are the cancer types where HSP90B2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.713	0.950	<.001	48	view →
SKCM	OS	Tertile	III,IV	0.494	0.220	<.001	46	view →
KICH	DFS	Quartile	III,IV	0.181	1.000	.003	43	view →
BRCA	DFS	Quartile	All	0.454	0.529	.006	42	view →
LUSC	DFS	Median	III,IV	0.445	0.935	<.001	40	view →
KIRC	DFS	Quartile	All	0.725	0.401	.002	32	view →
STAD	DFS	Tertile	IV	0.125	0.740	.002	31	view →
COAD	DFS	Tertile	All	0.712	0.477	.008	27	view →
KIRP	DFS	Median	All	0.556	0.652	.012	25	view →
THCA	DFS	Median	All	0.969	0.900	.003	20	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	18	view →
LAML	DFS	Quartile	All	0.670	0.441	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

HSP90B2P–ACC (OS)

Open the ACC breakdown →