HSP90AB1

Across TCGA patient cohorts, HSP90AB1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,452 significant associations in total. THYM shows the largest number of these associations.

The most reproducible HSP90AB1-associated genes across cancer lineages are NAA25, NCL, and UTP20. Each is linked with HSP90AB1 in more than 33 cancer types. Because this analysis shows association rather than direction, both HSP90AB1-to-partner and partner-to-HSP90AB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSP90AB1 versus NAA25 in DLBC, with a Pearson correlation of 0.58.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSP90AB1→partner) and Y-score (partner→HSP90AB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	NAA25 →	+1.310	+0.880	<.001	.001	3	34
UCEC	NCL →	+0.928	+0.936	<.001	<.001	3	34
DLBC	UTP20 →	+1.586	+0.919	<.001	<.001	3	34
TGCT	XPO5 →	+1.162	+1.002	<.001	<.001	3	34
ACC	NOL11 →	+1.093	+1.134	<.001	<.001	3	34
DLBC	NUP205 →	+1.415	+0.800	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,452 associations by consensus.

HSP90AB1 vs NAA25 — DLBC

Explore this scatter interactively →