HSFY1

Across TCGA cell cohorts, HSFY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 147 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HSFY1-associated GO terms across cancer lineages are Heme transport, Lipid droplet disassembly, and Response to lead ion. Each is linked with HSFY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSFY1-to-partner and partner-to-HSFY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heme transport grouped by HSFY1-low versus HSFY1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSFY1→partner) and Y-score (partner→HSFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Heme transport →	+0.075	+0.010	.003	.002	3	2
BLOOD_Leukemia	Lipid droplet disassembly →	+0.098	+0.014	<.001	<.001	3	2
BLOOD_Leukemia	Response to lead ion →	+0.102	+0.015	<.001	.002	3	1
BLOOD_Leukemia	Promoter clearance during DNA-templated transcription →	+0.045	+0.015	.009	<.001	3	1
BLOOD_Leukemia	RNA polymerase II promoter clearance →	+0.045	+0.015	.009	<.001	3	1
BLOOD_Leukemia	Neuroinflammatory response →	+0.069	+0.012	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 147 associations by consensus.

Heme transport by HSFY1 expression — BLOOD_Leukemia

Explore this box plot interactively →