HSFX3

Across TCGA patient cohorts, HSFX3 RNA expression is significantly associated with the protein abundance of many other proteins, with 2,651 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSFX3-associated proteins across cancer lineages are ARFGEF3_S1856, SAV1_S90, and ARL15. Each is linked with HSFX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSFX3-to-partner and partner-to-HSFX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSFX3 versus ARFGEF3_S1856 in LSCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSFX3→partner) and Y-score (partner→HSFX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARFGEF3_S1856 →	-0.512	-0.056	.003	.001	3	2
BRCA	SAV1_S90 →	-0.254	-0.109	.002	.006	3	2
GBM	ARL15 →	+0.250	+0.078	.001	.001	3	2
OV	MRPS36_S61 →	+0.723	+0.092	.003	.003	3	2
LUAD	MKI67_S3253 →	+1.699	+0.118	<.001	.002	3	1
LUAD	MSH6_S254 →	+2.003	+0.196	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,651 associations by consensus.

HSFX3 vs ARFGEF3_S1856 — LSCC

Explore this scatter interactively →