HSF2BP

Across TCGA patient cohorts, HSF2BP mutation is significantly associated with the RNA expression of many other genes, with 1,723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSF2BP-associated genes across cancer lineages are RN7SKP286, OR6N1, and OR6C76. Each is linked with HSF2BP in more than 1 cancer types. Because this analysis shows association rather than direction, both HSF2BP-to-partner and partner-to-HSF2BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP286 grouped by HSF2BP-low versus HSF2BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSF2BP→partner) and Y-score (partner→HSF2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP286 →	+0.053	+4.253	<.001	.004	3	2
SKCM	OR6N1 →	+0.053	+4.979	.001	.009	3	1
LUAD	OR6C76 →	+0.069	+5.798	<.001	.003	3	1
LUAD	RNA5SP505 →	+0.957	+6.444	<.001	.001	3	1
LUAD	RNU6-1222P →	+0.678	+5.099	<.001	.008	3	1
LUAD	CEACAMP8 →	+0.173	+5.217	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,723 associations by consensus.

RN7SKP286 by HSF2BP expression — UCEC

Explore this box plot interactively →