HSDL2

Across TCGA patient cohorts, HSDL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,727 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSDL2-associated proteins across cancer lineages are BSPRY, HSP90B1, and MMP14. Each is linked with HSDL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSDL2-to-partner and partner-to-HSDL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSDL2 versus BSPRY in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSDL2→partner) and Y-score (partner→HSDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BSPRY →	+0.703	+0.770	<.001	<.001	3	7
LUAD	HSP90B1 →	-0.473	-0.679	<.001	<.001	3	6
BRCA	MMP14 →	-0.454	-0.554	<.001	<.001	3	6
PDAC	STRBP →	+0.386	+0.463	<.001	<.001	3	6
BRCA	FAM120A →	+0.176	+0.566	<.001	<.001	3	6
CCRCC	DDAH1 →	+0.621	+0.607	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,727 associations by consensus.

HSDL2 vs BSPRY — UCEC

Explore this scatter interactively →