HSDL1

Across TCGA patient cohorts, HSDL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,552 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HSDL1-associated genes across cancer lineages are USP10, ATMIN, and MBTPS1. Each is linked with HSDL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSDL1-to-partner and partner-to-HSDL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSDL1 versus USP10 in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSDL1→partner) and Y-score (partner→HSDL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	USP10 →	+0.613	+0.415	<.001	<.001	3	7
OV	ATMIN →	+0.555	+0.611	<.001	<.001	3	7
OV	MBTPS1 →	+0.598	+0.409	<.001	<.001	3	6
OV	SPATA33 →	+0.605	+0.567	<.001	<.001	3	6
OV	KATNB1 →	+0.736	+0.627	.001	<.001	3	6
OV	HSBP1 →	+0.734	+0.465	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,552 associations by consensus.

HSDL1 vs USP10 — OV

Explore this scatter interactively →