Across TCGA cell cohorts, HSD3B2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible HSD3B2-associated genes across cancer lineages are RNASE9, CCL23, and OR4E1. Each is linked with HSD3B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD3B2-to-partner and partner-to-HSD3B2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD3B2→partner) and Y-score (partner→HSD3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	CCL23 →	+0.065	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4E1 →	+0.013	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

HSD3B2 survival (RNA) · tumor vs normal (RNA) · all HSD3B2 data types