Across TCGA patient cohorts, HSD17B8 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,893 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD17B8-associated proteins across cancer lineages are CBR4, DDB1, and CEP170. Each is linked with HSD17B8 in more than 6 cancer types. Because this analysis shows association rather than direction, both HSD17B8-to-partner and partner-to-HSD17B8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B8→partner) and Y-score (partner→HSD17B8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CBR4 →	+0.614	+0.844	<.001	<.001	3	7
LSCC	DDB1 →	+0.171	+0.513	<.001	<.001	3	7
GBM	CEP170 →	-0.280	-0.568	.009	<.001	3	6
BRCA	TKFC →	+0.423	+0.785	<.001	<.001	3	6
LUAD	DYNLL2 →	+0.355	+0.697	<.001	<.001	3	5
CCRCC	GFPT2 →	-0.812	-0.679	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,893 associations by consensus.

Exploration

HSD17B8 survival (RNA) · tumor vs normal (RNA) · all HSD17B8 data types