Across TCGA patient cohorts, HSD17B8 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,290 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HSD17B8-associated proteins across cancer lineages are GLUD1, HADHB, and HIBCH. Each is linked with HSD17B8 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSD17B8-to-partner and partner-to-HSD17B8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B8→partner) and Y-score (partner→HSD17B8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GLUD1 →	+0.596	+0.658	<.001	<.001	3	10
LUAD	HADHB →	+0.367	+0.509	<.001	<.001	3	10
LUAD	HIBCH →	+0.565	+0.422	<.001	<.001	3	10
OV	BCKDHB →	+0.589	+0.483	<.001	.002	3	10
OV	CBR4 →	+0.982	+0.916	<.001	<.001	3	10
GBM	ALDH5A1 →	+0.710	+0.473	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,290 associations by consensus.

Exploration

HSD17B8 survival (RNA) · tumor vs normal (RNA) · all HSD17B8 data types