Across TCGA patient cohorts, HSD17B8 mutation is significantly associated with the RNA expression of many other genes, with 436 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD17B8-associated genes across cancer lineages are RN7SL107P, HMGN1P9, and MIR941-5. Each is linked with HSD17B8 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B8-to-partner and partner-to-HSD17B8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B8→partner) and Y-score (partner→HSD17B8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL107P →	+0.173	+5.771	<.001	.003	3	1
SKCM	HMGN1P9 →	+0.164	+5.680	<.001	.003	3	1
SKCM	MIR941-5 →	+0.569	+6.469	<.001	.001	3	1
SKCM	MIR6752 →	+0.570	+6.199	<.001	.001	3	1
BLCA	TRAJ61 →	+1.141	+5.899	<.001	.002	3	1
UCEC	ZNHIT3 →	+0.626	+3.343	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 436 associations by consensus.

Exploration

HSD17B8 survival (RNA) · tumor vs normal (RNA) · all HSD17B8 data types