HSD17B7P1

Across TCGA pan-cancer cohorts, HSD17B7P1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated HSD17B7P1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HSD17B7P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HSD17B7P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.

KIRC, ACC, and LGG are the cancer types where HSD17B7P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	36	view →
ACC	DFS	Tertile	All	0.094	0.634	.002	27	view →
LGG	OS	Tertile	All	0.737	0.898	.002	24	view →
ESCA	OS	Median	II,III,IV	0.791	0.626	.011	23	view →
UVM	OS	Tertile	III,IV	0.136	0.874	<.001	15	view →
SKCM	DFS	Tertile	All	0.090	0.214	.023	12	view →
GBM	DFS	Tertile	All	0.181	0.271	.040	9	view →
OV	OS	Tertile	III,IV	0.744	0.654	.028	8	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

HSD17B7P1–KIRC (DFS)

Open the KIRC breakdown →