HSD17B6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HSD17B6 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,276 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HSD17B6-associated proteins across cancer lineages are VCL_S346, FERMT2, and GSN. Each is linked with HSD17B6 in more than 8 cancer types. Because this analysis shows association rather than direction, both HSD17B6-to-partner and partner-to-HSD17B6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B6 versus VCL_S346 in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B6→partner) and Y-score (partner→HSD17B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAVCL_S346 →+0.566+0.749<.001<.00139
UCECFERMT2 →+0.768+0.918<.001<.00139
OVGSN →+0.750+1.467<.001<.00139
CCRCCLMCD1 →+0.727+0.586<.001<.00139
UCECLPP →+0.811+1.018<.001<.00139
UCECPRKG1 →+0.824+0.768<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,276 associations by consensus.

HSD17B6 vs VCL_S346 — BRCA

Per-sample scatter of HSD17B6 vs VCL_S346 in BRCA (Pearson r = 0.45).

Explore this scatter interactively →

Exploration