HSD17B6

Across TCGA patient cohorts, HSD17B6 protein abundance is significantly associated with the RNA expression of many other genes, with 11,806 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD17B6-associated genes across cancer lineages are HOPX, NINJ2, and LRRK2. Each is linked with HSD17B6 in more than 2 cancer types. Because this analysis shows association rather than direction, both HSD17B6-to-partner and partner-to-HSD17B6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B6 versus HOPX in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B6→partner) and Y-score (partner→HSD17B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HOPX →	+1.964	+0.944	<.001	.003	3	3
OV	NINJ2 →	+1.005	+0.803	.009	<.001	3	3
LSCC	LRRK2 →	+1.489	+0.654	<.001	<.001	3	3
LSCC	SFTA2 →	+1.677	+0.677	<.001	<.001	3	3
OV	TPSB2 →	+1.554	+0.942	.002	.001	3	3
LUAD	RPL26P30 →	+0.911	+0.734	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,806 associations by consensus.

HSD17B6 vs HOPX — OV

Explore this scatter interactively →