HSD17B3

Across TCGA patient cohorts, HSD17B3 RNA expression is significantly associated with the RNA expression of many other genes, with 14,100 significant associations in total. UVM shows the largest number of these associations.

The most reproducible HSD17B3-associated genes across cancer lineages are RNU6-1160P, HSD17B3-AS1, and CCNL2. Each is linked with HSD17B3 in more than 31 cancer types. Because this analysis shows association rather than direction, both HSD17B3-to-partner and partner-to-HSD17B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B3 versus RNU6-1160P in CHOL, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B3→partner) and Y-score (partner→HSD17B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	RNU6-1160P →	+1.332	+1.545	<.001	<.001	3	32
ACC	HSD17B3-AS1 →	+0.699	+1.544	<.001	<.001	3	32
KIRC	CCNL2 →	+1.704	+1.223	<.001	<.001	3	24
KIRC	LYG1 →	+1.170	+0.382	<.001	<.001	3	24
KIRC	DPH7 →	+0.692	+1.019	<.001	<.001	3	24
KIRC	DNHD1 →	+0.951	+1.210	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,100 associations by consensus.

HSD17B3 vs RNU6-1160P — CHOL

Explore this scatter interactively →