HSD17B3

Across TCGA patient cohorts, HSD17B3 protein abundance is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD17B3-associated genes across cancer lineages are CKM, ATP4A, and DNTT. Each is linked with HSD17B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B3-to-partner and partner-to-HSD17B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B3 versus CKM in LSCC, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B3→partner) and Y-score (partner→HSD17B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CKM →	-0.219	-0.900	.009	<.001	1	1
LSCC	ATP4A →	-0.765	-0.900	.006	<.001	1	1
LSCC	DNTT →	+0.055	+0.900	.008	<.001	1	1
LSCC	TNFAIP1 →	-0.415	-0.900	.001	<.001	1	1
LSCC	ALDOC →	-0.585	-0.900	.004	<.001	1	1
LSCC	ZBTB32 →	-1.090	-0.900	.004	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

HSD17B3 vs CKM — LSCC

Explore this scatter interactively →