HSD17B3-AS1

Across TCGA patient cohorts, HSD17B3-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,116 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible HSD17B3-AS1-associated GO terms across cancer lineages are Regulation of protein neddylation, Organelle disassembly, and Negative regulation of TORC1 signaling. Each is linked with HSD17B3-AS1 in more than 25 cancer types. Because this analysis shows association rather than direction, both HSD17B3-AS1-to-partner and partner-to-HSD17B3-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein neddylation grouped by HSD17B3-AS1-low versus HSD17B3-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B3-AS1→partner) and Y-score (partner→HSD17B3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein neddylation →	+0.055	+0.146	<.001	<.001	3	25
STAD	Organelle disassembly →	+0.054	+0.149	<.001	<.001	3	25
STAD	Negative regulation of TORC1 signaling →	+0.050	+0.143	<.001	<.001	3	25
STAD	Protein stabilization →	+0.054	+0.152	<.001	<.001	3	25
ESCA	Glycerophospholipid metabolic process →	+0.049	+0.290	<.001	<.001	2	26
STAD	Protein localization to vacuole →	+0.056	+0.163	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,116 associations by consensus.

Regulation of protein neddylation by HSD17B3-AS1 expression — STAD

Explore this box plot interactively →