HSD17B14

Across TCGA cell cohorts, HSD17B14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,174 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HSD17B14-associated GO terms across cancer lineages are Positive regulation of TORC1 signaling, Regulation of TORC1 signaling, and Cardiac muscle cell action potential. Each is linked with HSD17B14 in more than 9 cancer types. Because this analysis shows association rather than direction, both HSD17B14-to-partner and partner-to-HSD17B14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of TORC1 signaling grouped by HSD17B14-low versus HSD17B14-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B14→partner) and Y-score (partner→HSD17B14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of TORC1 signaling →	+0.073	+2.037	.001	<.001	3	10
STOMACH	Regulation of TORC1 signaling →	+0.085	+2.465	<.001	<.001	3	9
BREAST	Cardiac muscle cell action potential →	-0.083	-0.846	.004	.006	3	9
LUNG_NSCLC_LUSC	Regulation of respiratory gaseous exchange by nervous system process →	+1.301	+2.040	<.001	<.001	3	8
LIVER	Positive regulation of hemostasis →	-0.293	-2.844	<.001	<.001	3	8
LIVER	Positive regulation of blood coagulation →	-0.293	-2.844	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,174 associations by consensus.

Positive regulation of TORC1 signaling by HSD17B14 expression — STOMACH

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