HSD17B10

Across TCGA patient cohorts, HSD17B10 protein abundance is significantly associated with the RNA expression of many other genes, with 12,613 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HSD17B10-associated genes across cancer lineages are CEACAM3, CSF3R, and TREM1. Each is linked with HSD17B10 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD17B10-to-partner and partner-to-HSD17B10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD17B10 versus CEACAM3 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B10→partner) and Y-score (partner→HSD17B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CEACAM3 →	-0.676	-0.246	<.001	<.001	3	6
COAD	CSF3R →	-1.412	-0.532	<.001	<.001	3	5
LSCC	TREM1 →	-0.961	-0.259	<.001	<.001	3	5
COAD	FCGR3B →	-1.831	-0.492	<.001	<.001	3	5
UCEC	CXCL3 →	-1.006	-0.284	<.001	<.001	3	5
PDAC	CXCL5 →	-2.538	-0.440	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,613 associations by consensus.

HSD17B10 vs CEACAM3 — LSCC

Explore this scatter interactively →