HSD17B10

Across TCGA patient cohorts, HSD17B10 mutation is significantly associated with the RNA expression of many other genes, with 828 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSD17B10-associated genes across cancer lineages are RNU6-1067P, IGLV3-31, and NTAN1P1. Each is linked with HSD17B10 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSD17B10-to-partner and partner-to-HSD17B10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1067P grouped by HSD17B10-low versus HSD17B10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B10→partner) and Y-score (partner→HSD17B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1067P →	+0.343	+2.716	<.001	.001	3	2
UCEC	IGLV3-31 →	+0.321	+2.560	<.001	<.001	3	2
UCEC	NTAN1P1 →	+0.103	+3.800	<.001	<.001	3	2
COAD	LINC01707 →	+0.231	+5.693	<.001	.003	3	2
UCEC	MIR6803 →	+0.172	+4.671	<.001	.002	3	2
BLCA	DBF4P3 →	+0.108	+7.040	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 828 associations by consensus.

RNU6-1067P by HSD17B10 expression — UCEC

Explore this box plot interactively →