HSD17B10

Across TCGA cell cohorts, HSD17B10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,684 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible HSD17B10-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of positive chemotaxis, and Mitotic sister chromatid cohesion. Each is linked with HSD17B10 in more than 14 cancer types. Because this analysis shows association rather than direction, both HSD17B10-to-partner and partner-to-HSD17B10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by HSD17B10-low versus HSD17B10-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD17B10→partner) and Y-score (partner→HSD17B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.178	+1.436	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of positive chemotaxis →	-0.193	-1.322	.006	<.001	3	12
PANCREAS	Mitotic sister chromatid cohesion →	+0.127	+1.055	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome separation →	+0.137	+1.113	<.001	.001	3	12
LUNG_NSCLC_LUSC	Pericentric heterochromatin formation →	+0.145	+0.855	.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of positive chemotaxis →	-0.193	-1.322	.006	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,684 associations by consensus.

DNA replication initiation by HSD17B10 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →