HSD11B2

Across TCGA patient cohorts, HSD11B2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,690 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HSD11B2-associated proteins across cancer lineages are PPP1R18, RAB31, and POGZ. Each is linked with HSD11B2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HSD11B2-to-partner and partner-to-HSD11B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HSD11B2 versus PPP1R18 in LSCC, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HSD11B2→partner) and Y-score (partner→HSD11B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP1R18 →	-0.405	-0.872	<.001	<.001	3	6
LUAD	RAB31 →	-0.446	-1.306	<.001	<.001	3	6
LSCC	POGZ →	+0.269	+0.898	.001	<.001	3	5
LUAD	NFIA →	+0.356	+1.124	<.001	<.001	3	5
CCRCC	CYBC1 →	-0.359	-0.984	.001	.005	3	5
CCRCC	GFPT2 →	-1.002	-1.646	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,690 associations by consensus.

HSD11B2 vs PPP1R18 — LSCC

Explore this scatter interactively →