Across TCGA patient cohorts, HSBP1L1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HSBP1L1-associated genes across cancer lineages are MIR4727, LSP1P3, and RNU6-151P. Each is linked with HSBP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HSBP1L1-to-partner and partner-to-HSBP1L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HSBP1L1→partner) and Y-score (partner→HSBP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4727 →	+0.793	+4.551	<.001	.009	3	1
UCEC	LSP1P3 →	+0.704	+4.233	<.001	.009	3	1
UCEC	RNU6-151P →	+0.932	+4.326	<.001	.007	3	1
UCEC	MIR188 →	+0.488	+5.582	<.001	.002	3	1
UCEC	IGLJ5 →	+1.046	+4.937	<.001	.005	3	1
UCEC	TRAJ58 →	+1.214	+5.073	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

HSBP1L1 survival (RNA) · tumor vs normal (RNA) · all HSBP1L1 data types