HS3ST6

Across TCGA patient cohorts, HS3ST6 protein abundance is significantly associated with the RNA expression of many other genes, with 356 significant associations in total. OV shows the largest number of these associations.

The most reproducible HS3ST6-associated genes across cancer lineages are TRIP11, TLE6, and TNKS2. Each is linked with HS3ST6 in more than 1 cancer types. Because this analysis shows association rather than direction, both HS3ST6-to-partner and partner-to-HS3ST6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS3ST6 versus TRIP11 in OV, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST6→partner) and Y-score (partner→HS3ST6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRIP11 →	+1.025	+1.125	.006	.001	3	1
OV	TLE6 →	+1.130	+1.105	.008	<.001	3	1
OV	TNKS2 →	+1.153	+1.396	<.001	.007	3	1
OV	ARR3 →	+1.136	+1.489	.002	.006	3	1
OV	DYNC2I1 →	+1.433	+1.466	.006	.006	3	1
OV	TAS2R4 →	+2.173	+1.466	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 356 associations by consensus.

HS3ST6 vs TRIP11 — OV

Explore this scatter interactively →