HS3ST2

Across TCGA patient cohorts, HS3ST2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,141 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HS3ST2-associated proteins across cancer lineages are ADA2, NPL, and SDS. Each is linked with HS3ST2 in more than 6 cancer types. Because this analysis shows association rather than direction, both HS3ST2-to-partner and partner-to-HS3ST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS3ST2 versus ADA2 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST2→partner) and Y-score (partner→HS3ST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADA2 →	+0.595	+1.287	<.001	<.001	3	7
LUAD	NPL →	+0.671	+1.237	<.001	<.001	3	7
LUAD	SDS →	+0.667	+0.750	<.001	<.001	3	7
GBM	PLD3 →	+0.493	+1.488	<.001	<.001	3	6
CCRCC	ACP5 →	+0.581	+1.405	<.001	<.001	3	6
OV	APOE →	+0.598	+0.582	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,141 associations by consensus.

HS3ST2 vs ADA2 — LSCC

Explore this scatter interactively →