HS3ST2

Across TCGA patient cohorts, HS3ST2 protein abundance is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HS3ST2-associated genes across cancer lineages are MIR643, LINC00111, and RNU7-18P. Each is linked with HS3ST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HS3ST2-to-partner and partner-to-HS3ST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS3ST2 versus MIR643 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST2→partner) and Y-score (partner→HS3ST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR643 →	+1.956	+0.721	.009	.006	3	1
BRCA	LINC00111 →	-0.363	-0.647	.006	.009	3	1
BRCA	RNU7-18P →	-2.589	-0.880	.002	.009	3	1
BRCA	C22orf24 →	-0.150	-0.880	.005	.009	2	1
BRCA	JAG2 →	-1.594	-0.880	.009	.009	2	1
BRCA	WWOX →	-0.778	-0.880	.008	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

HS3ST2 vs MIR643 — BRCA

Explore this scatter interactively →