HS3ST2

Across TCGA cell cohorts, HS3ST2 RNA expression is significantly associated with the go_rna of many other GO terms, with 188 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible HS3ST2-associated GO terms across cancer lineages are Apoptotic process involved in development, Positive regulation of bone resorption, and Muscle cell migration. Each is linked with HS3ST2 in more than 2 cancer types. Because this analysis shows association rather than direction, both HS3ST2-to-partner and partner-to-HS3ST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic process involved in development grouped by HS3ST2-low versus HS3ST2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HS3ST2→partner) and Y-score (partner→HS3ST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Apoptotic process involved in development →	-0.097	-0.514	.005	.002	3	3
OVARY	Positive regulation of bone resorption →	-0.175	-0.131	<.001	.007	3	2
PANCREAS	Muscle cell migration →	+0.096	+0.297	.001	.006	3	2
BLOOD_Myeloma	Myeloid cell differentiation →	+0.033	+0.012	.006	.005	3	2
BLOOD_Myeloma	Cellular response to UV →	+0.055	+0.012	<.001	.005	3	2
LUNG_SCLC	Positive regulation of cold-induced thermogenesis →	+0.059	+0.678	.001	.007	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

Apoptotic process involved in development by HS3ST2 expression — LUNG_SCLC

Explore this box plot interactively →