HS2ST1

Across TCGA patient cohorts, HS2ST1 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,402 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HS2ST1-associated proteins across cancer lineages are MAN1B1, CLCC1, and GALNT1. Each is linked with HS2ST1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HS2ST1-to-partner and partner-to-HS2ST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HS2ST1 versus MAN1B1 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HS2ST1→partner) and Y-score (partner→HS2ST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAN1B1 →	+0.530	+0.756	<.001	<.001	3	7
UCEC	CLCC1 →	+0.511	+0.665	<.001	<.001	3	6
OV	GALNT1 →	+0.689	+0.472	<.001	.006	3	6
UCEC	GALNT2 →	+0.603	+0.584	<.001	<.001	3	6
PDAC	RER1 →	+0.428	+0.683	<.001	<.001	3	6
UCEC	TM9SF2 →	+0.716	+0.853	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,402 associations by consensus.

HS2ST1 vs MAN1B1 — UCEC

Explore this scatter interactively →